Meeting Title: 21st IUPAB Congress 2024 (IUPAB2024), Date: June 24 (Mon) – 28 (Fri),Venue: ICC Kyoto(Kyoto International Conference Center)

TIMETABLE/INVITED SPEAKERS/SYMPOSIUM/POSTER

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Plenary Lecture Keynote Lecture Awards Symposium Hands-on Training Session Poster ABA Symposium Morning Seminar BP Seminar Sponsored Symposium

Plenary Lecture

Plenary IUPAB Katchalsky Lecture

Plenary Lecture 1

13:30-14:20, Mon. 24 June    Room A

Takeharu Nagai
Chair：
Takeharu Nagai（Osaka University）
Feng Zhang
Exploration of Biological Diversity Speaker：Feng Zhang Core Member, Broad Institute of MIT and Harvard
Investigator, McGovern Institute for Brain Research, MIT
James and Patricia Poitras Professor of Neuroscience at MIT
Associate Professor, Departments of Brain and Cognitive Sciences and Biological Engineering, MIT
New York Stem Cell Foundation-Robertson Investigator

Plenary IUPAB Engstrom Lecture

Plenary Lecture 2

9:00-9:50, Wed. 26 June    Room A

Christina Sizun
Chair：
Christina Sizun（Université Paris Saclay）
Toshio Ando
Filming biomolecules in dynamic action by high-speed AFM Speaker：Toshio Ando Distinguished Professor, Nano Life Science Institute (WPI-NanoLSI), Kanazawa University

Plenary IUPAB Ramachandran Lecture

Plenary Lecture 3

9:00-9:50, Thu. 27 June JST/17:00-17:50, Wed. 26 June PDT    Room B-1

Nobuyasu Koga
Chair：
Nobuyasu Koga（Osaka University）
David Baker

Remote

Design of New Protein Functions using Deep Learning Speaker：David Baker （University of Washington）

Keynote Lecture

Keynote Lecture 1

Searching for Universal Laws in Evolved and Evolvable Complex Biological Systems

9:00-9:50, Tue. 25 June    Room B-1

Chun-Biu Li
Chair：
Chun-Biu Li（Stockholm University）
Kunihiko Kaneko
Searching for Universal Laws in Evolved and Evolvable Complex Biological Systems Speaker：Kunihiko Kaneko Professor, Niels Bohr Institute, University of Copenhagen Professor Emeritus of University of Tokyo.
Kunihiko Kaneko earned his Ph.D. in chaos theory from the University of Tokyo in 1984. His career includes postdoctoral research at Los Alamos National Laboratory, an Assistant/Associate Professorship at the University of Tokyo, and Stanislaw Ulam Fellow at Los Alamos. He served as a professor at the University of Tokyo (1994-2022) and then joined the NBI. He held directorial roles at the Universal Biology Institute and the Center for Complex Systems Biology, while he was a visiting professor at several institutions including Institute for Advanced Studies, Princeton, Ecole Normale Lyon, and Osaka University. He works in theoretical biophysics, to extract universal characteristics in hierarchical biological systems.

Keynote Lecture 2

Molecular simulations open a window into cellular dynamics

17:30-18:20, Wed. 26 June    Room A

Yuji Sugita
Chair：
Yuji Sugita（RIKEN）
Gerhard Hummer
Molecular simulations open a window into cellular dynamics Speaker：Gerhard Hummer Director, Department of Theoretical Biophysics, Max Planck Institute of Biophysics, Frankfurt am Main, Deutschland Professor of Biophysics, Department of Physics, Goethe University Frankfurt, Frankfurt am Main, Deutschland Senior Fellow, Frankfurt Institute of Advanced Studies, Frankfurt am Main, Germany
Gerhard Hummer studied physics at the University of Vienna, Austria (1985-1990). After PhD studies at the Max Planck Institute for Biophysical Chemistry (1990-1992), he joined the Los Alamos National Laboratory (USA) as a postdoctoral fellow (1993-1996) and then as group leader (1996-1999). In 1999, he moved to the National Institutes of Health (USA), where he became Chief of the Theoretical Biophysics Section in the Laboratory of Chemical Physics. In 2013 he was appointed director at the Max Planck Institute of Biophysics in Frankfurt, Germany. Gerhard Hummer uses molecular simulations and theory to study biological systems at the molecular scale.

Keynote Lecture 3

Cytoplasmic Dynamics and Mechanics in the Maturation and Aging of Mammalian Oocytes

17:30-18:20, Wed. 26 June    Room B-1

Jie Yan
Chair：
Jie Yan（National University of Singapore）
Rong Li
Cytoplasmic Dynamics and Mechanics in the Maturation and Aging of Mammalian Oocytes Speaker：Rong Li Dr. Rong Li received her BS and MS degrees from Yale University and PhD from the University of California, San Francisco. She is currently Bloomberg Distinguished Professor, Johns Hopkins University, and Distinguish Professor and Director of Mechanobiology Institute, National University of Singapore. She studies cellular dynamics and mechanics, focusing on understanding the morphogenesis, homeostasis, adaptation and aging of eukaryotic cells.

Keynote Lecture 4

Decoding regeneration using computer designed proteins

9:00-9:50, Fri. 28 June JST/17:00-17:50, Thu. 27 June PDT    Room B-1

Ikuko Fujiwara
Chair：
Ikuko Fujiwara（Nagaoka University of Technology）
Hannele Ruohola-Baker

Remote

Decoding regeneration using computer designed proteins Speaker：Hannele Ruohola-Baker Biochemistry, Institute for Stem Cell and Regenerative Medicine, University of Washington

Awards

BPS Award Lecture

Accurate Models for Interrogating and Engineering Biomolecular Condensates

16:40-17:30, Wed. 26 June    Room B-1

Kumiko Hayashi
Chair：
Kumiko Hayashi（The University of Tokyo）
Jennifer Pesanelli
Presenter：Jennifer Pesanelli （Biophysical Society）
Jerelle A. Joseph
Accurate models for interrogating and engineering biomolecular condensates Awardee：Jerelle A. Joseph Jerelle Joseph holds a PhD in Chemistry (Computational) from the University of Cambridge, and an MPhil in Chemistry and a BSc in Mathematics and Chemistry from the University of the West Indies. She conducted postdoctoral studies as a research fellow at King’s College Cambridge and in the lab of Rosana Collepardo. Currently, Jerelle is an Assistant Professor of Chemical and Biological Engineering at Princeton University. Her research group focuses on developing accurate computer models to investigate biomolecular organization and engineer intracellular compartments.

The Avanti Prize Lecture

From color-tuning to optogenetics: modeling the relationship between red-light absorption and fluorescence intensity in archaerhodopsins

17:00-17:40, Mon. 24 June    Room A

Manuel Prieto
Chair：
Manuel Prieto（University of Lisbon, Portugal）
Anthony Watts
Chair：
Anthony Watts（University of Oxford, UK）
Massimo Olivucci
Dynamics and Efficiency of Light Energy Conversion in the Primary Event in Vision Speaker：Massimo Olivucci （University of Siena）

The Bei Lecture

Nanozyme, a new biological catalyst and its applications

18:30-19:10, Thu. 27 June    Room A

Pingsheng Liu
Chair：
Pingsheng Liu（Institue of Biophysics, CAS）
Xiyun Yan
Nanozyme, a new biological catalyst and its applications Speaker：Xiyun Yan （Institute of Biophysics, Chinese Academy of Sciences）

The Young Investigator Award Lecture

Structural and functional diversity in light-gated ion channels: channelrhodopsins

16:00-16:40, Wed. 26 June    Room A

Manuel Prieto
Chair：
Manuel Prieto（University of Lisbon, Portugal）
Anthony Watts
Chair：
Anthony Watts（University of Oxford, UK）
Hideaki Kato
Structural and functional diversity in pump-like cation channelrhodopsins Speaker：Hideaki Kato （The University of Tokyo）

The 20th Early Career Award in Biophysics Candidate Presentations

10:00-12:20, Tue. 25 June    Room A

Takayuki Nishizaka
Chair：
Takayuki Nishizaka（Gakushuin University）
xxxxxx
Chair：
Shuji Akiyama（Institute for Molecular Science）
Hiroki Sakuta
Microtubule/kinesin complexes spontaneously emerge vortices in cell-sized droplet generated by water/water phase separation Speaker：Hiroki Sakuta （The University of Tokyo）
Hongjie Li
Oxygen-evolving photosystem II structures during S1–S2–S3 transitions Speaker：Hongjie Li （Okayama University）
Misa Minegishi
A high-throughput analysis of cancer-cell dormancy under mechanical confinement with micro-hydrogel beads Speaker：Misa Minegishi （RIKEN）
Daichi Takahashi
Crosstalk of two bacterial actins composed of the force generation unit of Spiroplasma swimming Speaker：Daichi Takahashi （Okayama University）
xxxxx
Spatiotemporal formation of a single liquid-like condensate of α-synuclein and subsequent aging by optical trapping Speaker：Keisuke Yuzu （Kobe University / National Yang Ming Chiao Tung University）
xxxxx
Encapsulation of cell nucleolus by single-stranded DNA Speaker：Koichiro Maki （Kyoto University）
Masayuki Hayakawa
From cellular chirality to large-scale chirality: Emergence of chiral spiral in migrating cellular system Speaker：Masayuki Hayakawa （RIKEN Center for Biosystems Dynamics Research）
Shuya Ishii
Myosin and tropomyosin-troponin complementarily regulate thermal activation of striated muscles Speaker：Shuya Ishii （National Institutes for Quantum Science and Technology）
Koji Ooka
Prediction of detailed structures over the entire free energy landscape of protein folding using extended statistical mechanical models and restrained simulations Speaker：Koji Ooka （The University of Tokyo）
Ryo Nishihara
Pseudo-luciferase activity of the SARS-CoV-2 spike protein Speaker：Ryo Nishihara （National Institute of Advanced
Industrial Science and
Technology (AIST)）

Symposium

Symposium 1

Super-resolution and Advanced Microscopy Imaging

14:30-16:50, Mon. 24 June    Room A

Katsumasa Fujita
Cryo-optical microscopy for super-resolution imaging of the moment Speaker：Katsumasa Fujita （Osaka University）
Tomomi Tani
3D architectural dynamics of super-molecular assembly in live cells by using single molecule orientation imaging with advanced fluorescence polarization probes Pick-up：Tomomi Tani （National Institute of Advanced Industrial Science and Technology）
Luciano Masullo
Ångström-resolution fluorescence microscopy Pick-up：Luciano Masullo （Max Planck Institute of Biochemistry）
Elizabeth Hinde
Fluorescence fluctuation spectroscopy of protein transport as a function of oligomeric state Chair / Speaker：Elizabeth Hinde （The University of Melbourne）
Michelle Digman
Biophysical Characterization of Cancer Metabolism: Multiparametric Imaging and Phenotypic Tracking in Mitochondrial Dynamics Speaker：Michelle Digman （University of California Irvine）
Takanobu Katoh
Immotile cilia mechanically sense the direction of fluid flow for left-right determination Chair / Speaker：Takanobu Katoh （The University of Tokyo）

Symposium 2

Morphogenesis during Development and Repair

14:30-16:50, Mon. 24 June    Room B-1

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Chair：
Satoru Okuda（Kanazawa University）
xxxxxx
Chair：
Yanlan Mao（University College London）
Chii Jou Chan
Mechano-hydraulic control of mammalian ovarian follicle development Speaker：Chii Jou Chan （Mechanobiology Institute）
Pablo Vicente Munuera
A 3D Vertex Model to analyse the Drosophila wing disc during wound healing Speaker：Pablo Vicente Munuera （University College London）
Misato Iwashita
Comparative study of interspecies diversity in cortical stiffness using atomic force microscopy Pick-up：Misato Iwashita （Korea Brain Research Institute）
Melissa Rinaldin
Robust cytoplasmic partitioning by resolving an intrinsic cytoskeletal instability Pick-up：Melissa Rinaldin （Physics of Life Excellence Cluster TU Dresden and MPI Molecular Cell Biology and Genetics）
Ritsuko Morita
“Telescope model” for coordinated organ morphogenesis and stem cell formation Speaker：Ritsuko Morita （Osaka University）
Caren Norden
The role of nuclear properties and packing for movements in pseudostratified epithelia Speaker：Caren Norden （Instituto Gulbenkian de Ciência）

Symposium 3

Cryo Electron Microscopy and Tomography

14:30-16:50, Mon. 24 June    Room B-2

Fei Sun
In-cell structure of microtubule doublet in mouse sperm flagella reveals the structural stability essential for motility Chair / Speaker：Fei Sun （CAS）
Masahide Kikkawa
Combination of genetics and cryo-electron tomography to study the calcium-dependent regulation of outer arm dynein in zebrafish sperm Chair / Speaker：Masahide Kikkawa （The University of Tokyo）
Ruchi Anand
Deciphering the Mechanism of Ribosomal Methylase Mediated Antibiotic Resistance Speaker：Ruchi Anand （Indian Intitute of Technology Bombay）
Kazuhiro Abe
Structural physiology of gastric proton pump and related cation pumps Speaker：Kazuhiro Abe （Nagoya University）
Gabriel Lander
CryoEM brings new mechanistic insights into double-stranded DNA break repair Speaker：Gabriel Lander （Scripps Research）
Yongchan Lee
Structural Studies of SLC Transporters Relevant to Health and Diseases Speaker：Yongchan Lee （Yokohama City University）

Symposium 4

Correlative Cell Imaging

14:30-16:50, Mon. 24 June    Room D

Tomonobu Watanabe
Chair：
Tomonobu Watanabe（RIKEN/Hiroshima University）
Ioanna Mela
Correlative Atomic Force Microscopy with Super-resolution Microscopy for the characterisation of biological specimens Chair / Speaker：Ioanna Mela （University of Cambridge）
Shotaro Otsuka
The endoplasmic reticulum connects to the nucleus by constricted junctions that mature after open mitosis in mammalian cells Speaker：Shotaro Otsuka （Max Perutz Labs, Vienna Biocenter）
Timothy Stasevic
From Transcription to Translation: Single Molecule Imaging of Endogenous Gene Activity Speaker：Timothy Stasevic （Colorado State University）
Guan-Yu Zhuo
Label-free correlative imaging reveals the heterogeneity of tumor microenvironments Speaker：Guan-Yu Zhuo （China Medical University）
Tokuko Haraguchi
Live CLEM imaging for studies of nuclear envelope dynamics Chair / Speaker：Tokuko Haraguchi （Osaka University）

Symposium 5

Theoretical Biology of Complex Systems

14:30-16:50, Mon. 24 June    Room E

Masayo Inoue
Chair：
Masayo Inoue（Kyushu Institute of Technology）
xxxxxx
Chair：
Chikara Furusawa（RIKEN）
Mikhail Tikhonov
Emergent simplicity in microbial ecosystems Chair / Speaker：Mikhail Tikhonov （Washington University）
Arvind Murugan
The origin of non-equilibrium order Speaker：Arvind Murugan （University of Chicago）
Anne-Florence Bitbol
Impact of population spatial structure on mutant fixation, from models on graphs to the gut Speaker：Anne-Florence Bitbol （EPFL）
Ken-Ichiro F. Kamei
Revealing global stoichiometry conservation architecture in cells by Raman and gene expression correspondences Pick-up：Ken-Ichiro F. Kamei （The University of Tokyo）
Yusuke Himeoka
Stability and death of in silico Escherichia coli metabolism Pick-up：Yusuke Himeoka （The University of Tokyo）

Symposium 6

Mechanosensing and Mechanobiology, Biological Temperature

10:00-12:20, Tue. 25 June    Room B-1

Kate Poole
Mammalian mechanosensing via ion channels Chair / Speaker：Kate Poole （University of New South Wales）
Satoshi Arai
Visualization and Control of Biological Temperature Using Subcellular-Targeted Chemical Dyes Speaker：Satoshi Arai （Kanazawa University）
xxxxx
Mechanotransduction at cell-cell junctions: beyond the usual suspects Speaker：Alexander Dunn （Stanford University）
Mitsuhiro Iwaki
DNA nanodevices for single-molecule biology in mechanosystems Chair / Speaker：Mitsuhiro Iwaki （National Institute of Information and Communications Technology）
Misa Minegishi
A high-throughput analysis of cancer-cell dormancy under mechanical confinement with micro-hydrogel beads Pick-up：Misa Minegishi （RIKEN）
Hendrik von Eysmondt
Platelet migration behavior is dependent on substrate stiffness Pick-up：Hendrik von Eysmondt （University of Tuebingen）

Symposium 7

Protein Structure to Function 1

10:00-12:20, Tue. 25 June    Room B-2

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Chair：
Mikako Shirouzu（RIKEN）
xxxxx
Structural dynamics of parathyroid hormone receptor and development of biased agonist Speaker：Osamu Nureki （The University of Tokyo）
Ho Min Kim
Structure and Function of TMEM87A, a unique Voltage-dependent Cation Channel in Golgi apparatus Chair / Speaker：Ho Min Kim （Korea Advanced Institute of Science and Technology）
Atsushi Yamagata
Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A Pick-up：Atsushi Yamagata （RIKEN）
xxxxx
Multi-dimensional crystallography: how do enzymes work? Speaker：Pedram Mehrabi （University of Hamburg）
Maria Selmer
SAM lyases – small, divergent and multifunctional proteins in bacteriophage counter defense Speaker：Maria Selmer （Uppsala University）
Kakoli Bose
Unraveling the Energy Transition Network That Dictates Allosteric Activation of Proapoptotic High-Temperature Requirement Protease A2 Speaker：Kakoli Bose （ACTREC, Tata Memorial Centre）

Symposium 8

Unstructured/Disordered Proteins, RNA

10:00-12:20, Tue. 25 June    Room C-2

Shintaro Iwasaki
Chair：
Shintaro Iwasaki（RIKEN）
Maria Hondele
DEAD-box ATPases are global regulators of phase-separated organelles and RNA flux Speaker：Maria Hondele （University of Basel）
Zoher Gueroui
Engineering phase separations in cells to manipulate RNA condensates Speaker：Zoher Gueroui （PSL University）
Yuichi Shichino
Transcriptomics in P-bodies reveals the selective mRNA release to modulate translation Speaker：Yuichi Shichino （RIKEN）
Tae Lim Park
Stress Granule Fusion Mediated by Mitochondrial Dynamics Is Essential for Cell Survival Pick-up：Tae Lim Park （Korea Advanced Institute of Science & Technology (KAIST)）
Yoshiko Nakagawa
Amyloid conformation-dependent disaggregation revealed by single-molecule fluorescence imaging Pick-up：Yoshiko Nakagawa （RIKEN）

Symposium 9

Lipid and Membrane Biophysics

10:00-12:20, Tue. 25 June    Room D

Chiho Watanabe
Exploring Lipid and Membrane Biophysics Chair / Speaker：Chiho Watanabe （Hiroshima University）
Luca Andronico
High-throughput analysis of membrane fluidity unveils a hidden dimension in immune cell states Speaker：Luca Andronico （Karolinska Institutet）
Sarah Veatch
Biological tuning of the membrane phase transition facilitates plasma membrane organization and function. Speaker：Sarah Veatch （University of Michigan）
Nishu Kanwa
Lipid heterogeneity within giant vesicles confer robust protein pattern formation Pick-up：Nishu Kanwa （Max Planck Institute for Biochemistry）
Masanao Kinoshita
Electron diffraction reveals substructures in lipid raft-like ordered membrane domains Pick-up：Masanao Kinoshita （Kyushu University）
Michihiro Nagao
Elastic and viscous properties of model lipid bilayers measured using dynamic neutron scattering Speaker：Michihiro Nagao （University of Maryland and NIST）
Roberto Covino
Investigating how membranes control the thermodynamics and kinetics of membrane protein complexes with molecular simulations. Chair / Speaker：Roberto Covino （Frankfurt Institute for Advanced Studies）

Symposium 10

Data Science for Integrated Dynamic Structural Biology

10:00-12:20, Tue. 25 June    Room E

Florence Tama
Chair：
Florence Tama（Nagoya University & RIKEN Center for Computational Science）
Jianhan Chen
Chair：
Jianhan Chen（University of Massachusetts Amherst）
Alexandre Bonvin
Solving 3D puzzles of biomolecular interactions by integrative modelling Speaker：Alexandre Bonvin （Utrecht University）
Chaok Seok
Searching the Molecular Space using Neural Network Energy Models Speaker：Chaok Seok （Seoul National University）
Mao Oide
Dynamic structure of monomeric Grb2 revealed via integrative modeling Pick-up：Mao Oide （RIKEN CPR）
Michael Feig
Dynamics of Intrinsically Disordered Proteins via Simulations and Machine Learning Speaker：Michael Feig （Michigan State University）
Massimiliano Bonomi
Protein structural ensembles from 3D and 2D cryo-EM data Speaker：Massimiliano Bonomi （Institut Pasteur - CNRS）

Symposium 11

Single Molecule Biophysics in Chromosome Science

16:00-18:20, Tue. 25 June    Room A

Kayo Hibino
Single-nucleosome imaging unveils dynamic organization of mitotic chromosomes. Chair / Speaker：Kayo Hibino （National Institute of Genetics）
Gijs JL Wuite
Mechanics and microrheology of native human mitotic chromosomes Speaker：Gijs JL Wuite （Vrije Universiteit Amsterdam）
Sotaro Uemura
Unpaused and Loosened Unwinding of Nucleosomal DNA on H2A.B Variants Pick-up：Sotaro Uemura （The University of Tokyo）
Ibrahim Cissé
Super-resolution imaging of transcription in living cells Speaker：Ibrahim Cissé （Max Planck Institute for Immunobioloy and Epigenetics）
Je-Kyung Ryu
Bridging-induced phase separation by cohesin complexes Chair / Speaker：Je-Kyung Ryu （Seoul National University）

Symposium 12

Cell Motility, Cytoskeleton and Motor Proteins

16:00-18:20, Tue. 25 June    Room B-1

Ikuko Fujiwara
Inhibitory mechanisms of actin polymerization dynamics at the molecular level by Cytochalasin D and Archea gelsolin Chair / Speaker：Ikuko Fujiwara （Nagaoka University of Technology）
Yuta Shimamoto
COLLECTIVE MOTOR AND MICROTUBULE MECHANICS UNDERLYING SPINDLE SELF-ORGANIZATION Speaker：Yuta Shimamoto （National Institute of Genetics）
Sarah Köster
Intermediate filaments in the cytoskeleton: safety belt and shock absorber for the cell? Chair / Speaker：Sarah Köster （University of Goettingen）
Paul Janmey
Intra- and extra-cellular functions of vimentin: mechanics, signaling, and adhesion Speaker：Paul Janmey （Univ. Pennsylvania）
Cécile Sykes
Cell biophysics: phase diagrams, phase portraits and trajectories Speaker：Cécile Sykes （Laboratoire de Physique de l'Ecole Normale Supérieure CNRS/ENS/Université Paris Cité and Sorbonne Université）

Symposium 13

Protein Structure to Function 2

16:00-18:20, Tue. 25 June    Room B-2

Shun-ichi Sekine
Structural basis of promoter-proximal pausing of RNA polymerase II at +1 nucleosome Chair / Speaker：Shun-ichi Sekine （RIKEN）
xxxxx
Coarse-grained molecular dynamics simulations of parental histone H3/H4 recycling by a replisome Pick-up：Fritz Nagae （Kyoto University）
Kayo Nozawa
Structural and biochemical analysis of a unique structural unit of chromatin Speaker：Kayo Nozawa （Tokyo Institute of Technology）
Christina Sizun
A dual interaction between RSV NS1 protein and MED25 underlies RSV virulence and interferon antagonism Pick-up：Christina Sizun （Université Paris Saclay）
Heeyoun Bunch
ERK2-topoisomerase II regulatory axis is important for gene activation in immediate early genes Chair / Speaker：Heeyoun Bunch （Kyungpook National University）
Won-Ki Cho
Topological formation of transcriptional condensates relative to subnuclear compartments Speaker：Won-Ki Cho （Korea Advanced Institute of Science & Technology (KAIST)）
Satoru Ide
Spatial regulation of ribosomal RNA transcription by phase separation and transition Speaker：Satoru Ide （National Institute of Genetics）

Symposium 14

Data Science, Machine Learning, and Analytical Frameworks for Understanding the Heterogeneity of Cellular and Multicellular Systems

16:00-18:20, Tue. 25 June    Room E

Susanne Rafelski
Integrated intracellular organization dynamics and its variations in human iPS cells Chair / Speaker：Susanne Rafelski （Allen Institute for Cell Science）
xxxxx
Machine learning interpretable models of cell mechanics and mophogenesis Speaker：Vincenzo Vitelli （University of Chicago）
xxxxx
Enhancing Identification of Cancer Stem Cells through Line Illumination Raman Microscopy and Hydrogel-Based Platforms Pick-up：Jean-Emmanuel Clement （WPI-ICReDD）
Shuhei Horiguchi
Cellular gradient flow structure connects single-cell-level rules and population-level dynamics Pick-up：Shuhei Horiguchi （Kanazawa University）
xxxxx
Imaged-based prediction of single-cell transcriptomic phenotypes using robotic data acquisition Chair / Speaker：Katsuyuki Shiroguchi （RIKEN）
Maria Brbic
Machine learning for Overcoming Heterogeneity of Single-cell Datasets Speaker：Maria Brbic （École Polytechnique Fédérale de Lausanne (EPFL)）

Symposium 15

Single Molecule Biophysics with Advanced Techniques

10:00-12:20, Wed. 26 June    Room A

Masataka Yanagawa
Unveiling receptor dynamics with single-molecule high-content analysis Chair / Speaker：Masataka Yanagawa （Tohoku University）
Ke Xu
Multidimensional Super-Resolution Microscopy of the Living Cell Speaker：Ke Xu （University of California, Berkeley）
Sangjin Kim
Subcellular localization and diffusion dynamics of RNA degradosome proteins in live bacteria cells Speaker：Sangjin Kim （University of Illinois at Urbana-Champaign）
Scott Blanchard
mRNA decoding in human is kinetically and structurally distinct from bacteria. Speaker：Scott Blanchard （St. Jude Children's Research Hospital）
Doory Kim
Ultrastructural Studies of Gram-positive Bacteria and Their Extracellular Vesicles Chair / Speaker：Doory Kim （Hanyang University）

Symposium 16

Rotary ATPases

10:00-12:20, Wed. 26 June    Room B-1

Tomoko Masaike
Mechanisms of rotary ATPases Chair / Speaker：Tomoko Masaike （Tokyo University of Science）
Alastair Stewart
E. coli ATP synthase after the addition of ATP or ADP Chair / Speaker：Alastair Stewart （The Victor Chang Cardiac Research Institute）
David Sivak
Inferring subsystem efficiencies in bipartite molecular machines Speaker：David Sivak （Simon Fraser University）
Yoshiaki Kinosita
Biophysical characterization of the archaellar motor rotation Speaker：Yoshiaki Kinosita （RIKEN）
Stephan Wilkens
Molecular Mechanism of V-ATPase Reversible Disassembly Speaker：Stephan Wilkens （SUNY Upstate Medical University）
Akihiro Otom
Sodium motive force-driven ATP synthesis by EhV-ATPase Pick-up：Akihiro Otomo （Institute for Molecular Science）
Hiroshi Ueno
Engineering of ATP synthase to enhance proton-to-ATP ratio Speaker：Hiroshi Ueno （The University of Tokyo）

Symposium 17

Protein Design & Engineering

10:00-12:20, Wed. 26 June    Room B-2

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Chair：
Ai Niitsu（RIKEN）
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Modular protein design for new protein folds and regulation of protein and biological processes Speaker：Roman Jerala （National Instritute of Chemistry）
xxxxx
Indels: The Evolutionary Switches Bridging Protein Functions and Topologies Speaker：Paola Laurino （Okinawa Inst. of Sci. & Tech. Graduate Univ.）
Guto Rhys
How will we catalyse unnatural reactions using proteins? Chair / Speaker：Guto Rhys （Cardiff University）
Masaharu Somiya
Computational design of highly active SNARE-like membrane fusion proteins Pick-up：Masaharu Somiya （SANKEN, Osaka University）
Minkyung Baek
Protein Structure Prediction and Design using RoseTTAFold Speaker：Minkyung Baek （Seoul National University）
Teppei Deguchi
Data Efficient Protein Function Improvement by Machine Learning with Molecular Simulation Pick-up：Teppei Deguchi （The University of Tokyo）

Symposium 18

Neural Systems and Excitable Cells

10:00-12:20, Wed. 26 June    Room C-2

Klaus Gerwert
Aβ-MISFOLDING AS PRECISE RISK PLASMA BIOMARKER FOR ALZHEIMER DEMENTIA IN A SYMPTOM-FREE STAGE Speaker：Klaus Gerwert （Ruhr-University Bochum & Centre for Protein Diagnsotics (PRODI)）
xxxxx
Harnessing thermoplasmonics to modulate neuronal excitability and network activity Speaker：Yoonkey Nam （KAIST(Korea Advanced Institute of Science and Technology)）
Sung Hyun Kim
Distinct synaptic vesicle recycling in inhibitory nerve terminals is coordinated by SV2A Chair / Speaker：Sung Hyun Kim （Kyung Hee University）
：Chie Hosokawa
Optical Manipulation of Molecular Dynamics in Neurons Chair / Speaker：Chie Hosokawa （Osaka Metropolitan University）
Aylin Balmes
Measuring the stiffness of neuronal growth cones with scanning ion conductance microscopy Pick-up：Aylin Balmes （University Tübingen）
Asahi Nakamuta
Optimal power-law encoding is self-organized in cultured neuronal networks Pick-up：Asahi Nakamuta （Kyoto University）

Symposium 19

Understanding Structure and Function of Emerging Viruses

10:00-12:20, Wed. 26 June    Room D

Katsumi Maenaka
Chair：
Katsumi Maenaka（Hokkaido University）
Shang-Te Danny Hsu
Functional annotation of viral protein sugarcoats Speaker：Shang-Te Danny Hsu （Academia Sinica）
Peter J. Bond
Host Recognition of SARS-CoV-2 Spike: A Double-Edged Sword Pick-up：Peter J. Bond （Bioinformatics Institute (BII) A*STAR）
Sai Li
Cryo-ET of SARS-CoV-2 provided insights into its architecture and neutralization Speaker：Sai Li （Tsinghua University）
Hisham Dokainish
Elucidating Spike Protein Conformations from Simulation and Experiment Speaker：Hisham Dokainish （Hokkaido University）
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Direct inhibition of human APOBEC3 deaminases by HIV-1 Vif independent of the ubiquitination/degradation pathway Pick-up：Keisuke Kamba （Kyoto University）
Juha Huiskonen
Restructuring of bacteriophage ɸ6 viral particle activates semi-conservative transcription Chair / Speaker：Juha Huiskonen （University of Helsinki）

Symposium 20

Synthetic and Constructive Biology

10:00-12:20, Wed. 26 June    Room E

Tomoaki Matsuura
Chair：
Tomoaki Matsuura（Tokyo Institute of Technology）
xxxxx
A potential path to the Darwinian evolution of protocells Chair / Speaker：Sheref S. Mansy （University of Alberta）
Yutetsu Kuruma
Design and construction of artificial cells reproducing cellular functions Speaker：Yutetsu Kuruma （Japan Agency for Marine-Earth Science and Technology）
Karen Polizzi
SUGARS FOR FUNCTION: Enabling protein post-translational modifications in cell-free systems Speaker：Karen Polizzi （Imperial College London）
Constance B. Bailey
Pigment Reporters for Further Development of Cell Free Systems for Synthetic Biology with Secondary Metabolism Speaker：Constance B. Bailey （University of Sydney）
Ken'ya Furuta
Synthetic approaches to biomolecular motors Speaker：Ken'ya Furuta （NiCT）

Symposium 21

Computational Molecular Biophysics

10:00-12:20, Thu. 27 June    Room A

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Chair：
Cecilia Clementi（Freie Universität Berlin）
José Onuchic
Modeling the Genome: A View by a Physicist Speaker：José Onuchic （Rice University）
Rosana Collepardo-Guevara
Physicochemical regulation of the liquid-like organisation of chromatin Speaker：Rosana Collepardo-Guevara （University of Cambridge）
Diego Ferreiro
Solvent constraints for biopolymer folding and evolution in extraterrestrial environments Speaker：Diego Ferreiro （Univ Buenos Aires）
Young Min Rhee
Changes in VEGFR by VEGF: Pursuing activation mechanism and drug targeting via computer simulations Speaker：Young Min Rhee （Korea Advanced Institute of Science and Technology）
Shoji Takada
Multiscale biomolecular simulations for chromatin and transcription regulation Chair / Speaker：Shoji Takada （Kyoto University）

Symposium 22

Bacterial/Archaeal Supermolecular Assembly

10:00-12:20, Thu. 27 June    Room B-1

Daisuke Nakane
Chair：
Daisuke Nakane（The University of Electro-Communications）
Annegret Wilde
Phototaxis and control of type IV pilus functions Speaker：Annegret Wilde （University of Freiburg）
Shingo Kato
Cell surface architecture of a nano-sized archaeon Nanobdella aerobiophila Speaker：Shingo Kato （RIKEN-BRC）
Isil Tulum
Development of Protein-Based Strategies for Detection, Identification and Controlling Plant Pathogenic Phytoplasmas Chair / Speaker：Isil Tulum （Istanbul University）
xxxxx
Coevolution of glycosylation, flagellar motor and cell shape in Campylobacter jejuni for efficient host Speaker：Eli Cohen （Imperial College London）
Anna Roujeinikova
Dissecting the structure and function of the bacterial flagellar motor. Pick-up：Anna Roujeinikova （Monash University）
Shufeng Zhao
From Inactivity to Motion: Uncovering Motility Dynamics of Alcanivorax Borkumensis Pick-up：Shufeng Zhao （University of Tsukuba）

Symposium 23

Optogenetics and Photobiology

10:00-12:20, Thu. 27 June    Room B-2

Keiichi Inoue
Chair：
Keiichi Inoue（The University of Tokyo）
Kota Katayama
Chair：
Kota Katayama（Nagoya Institute of Technology）
xxxxx
The search for new carotenoid light-harvesting systems in microbial rhodopsins Speaker：Oded Béjà （Technion-Israel Institute of Technology）
John T.M. Kennis
MULTIPLE RETINAL ISOMERIZATIONS DURING THE EARLY PHASE OF THE BESTRHODOPSIN PHOTOREACTIONS Speaker：John T.M. Kennis （Vrije Universiteit Amsterdam）
Eriko Nango
Structural Dynamics of Microbial Rhodopsins Captured by X-ray Free Electron Lasers Speaker：Eriko Nango （Tohoku university）
Igor Schapiro
Photoisomerization Mechanism of Retinal in Different Microbial Rhodopsins - Insight from Multiscale Simulation Speaker：Igor Schapiro （Hebrew University of Jerusalem）
Akihisa Terakita
Coral opsins: unique spectral tuning and G protein selectivity Speaker：Akihisa Terakita （Osaka Metropolitan University）

Symposium 24

Chromatin Dynamics and Imaging

10:00-12:20, Thu. 27 June    Room C-2

Vadim Backman
Chromatin domains as an emergent property: how cells learn to regulate epigenetic memory and transcriptional reprogramming Chair / Speaker：Vadim Backman （Northwestern University）
Kazuhiro Maeshima
Replication-dependent histone (Repli-Histo) labeling specifically visualizes physical properties of euchromatin/heterochromatin in living human cells. Chair / Speaker：Kazuhiro Maeshima （National Insitute of Genetics）
Barak Cohen
Understanding the Regulatory Grammar of Enhancers and Silencers: Biophysical Insights from Machine Learning Speaker：Barak Cohen （Washington University in St. Louis）
Olga K. Dudko
What phase of matter is the chromosome -- and why should the living cell care? Speaker：Olga K. Dudko （University of California, San Diego）
Jan Huertas
THE PIONEER TRANSCRIPTION FACTOR OCT4 ALTERS CHROMATIN PACKING Pick-up：Jan Huertas （University of Cambridge）

Symposium 25

Biophysics of Disease

10:00-12:20, Thu. 27 June    Room D

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Engineered chaperone-mediated disaggregation and degradation of yeast prions Chair / Speaker：Motomasa Tanaka （RIKEN Center for Brain Science）
Joost Schymkowitz
How heterotypic amyloid interactions determine amyloid pathology Speaker：Joost Schymkowitz （VIB-KULeuven）
David Boyer
Visualizing Amyloid Oligomers, the Dark Matter of Alzheimer’s Disease Speaker：David Boyer （UCLA）
xxxxx
Unveiling the Mechanism of Protein Aggregation to Form Oligomers and Protofibrils: A Study Using Insulin as a Model Chair / Speaker：Eri Chatani （Kobe University）
xxxxx
Chemical and structural bases for fibril aggregate formation of RNA-binding proteins with low-complexity domains by neurodegenerative disease mutations. Speaker：Masato Kato （University of Texas Southwestern Medical Center）
Yun-Ru (Ruby) Chen
Investigation of Toxicity and Structural Mechanism of Dipeptide Repeats in ALS and the Therapeutic Strategy Speaker：Yun-Ru (Ruby) Chen （Academia Sinica）
Lukasz Joachimiak
Engineering proteins to control amyloid assembly Chair / Speaker：Lukasz Joachimiak （University of Texas Southwestern Medical Center）
Gabriella Viero
Unlocking Ribosome Heterogeneity: High-Resolution Genome-Wide Positional Sequencing and Its Implications in Disease Research Speaker：Gabriella Viero （Institute of Biophysics）

Symposium 26

Applications of Non-equilibrium Physics

16:00-18:20, Thu. 27 June    Room B-1

Kumiko Hayashi
Chair：
Kumiko Hayashi（The University of Tokyo）
Chun-Biu Li
Chair：
Chun-Biu Li（Stockholm University）
Huijuan You
Kinetic basis of G-quadruplex selective stabilizing ligands revealed by single-molecule manipulation Pick-up：Huijuan You （Huazhong University of Science and Technology）
Takayuki Ariga
Nonequilibrium energetics and noise-induced acceleration of molecular motor, kinesin-1 Speaker：Takayuki Ariga （Osaka University）
xxxxx
Active fluctuations of cytoplasmic actomyosin networks facilitate dynein-driven intracellular transports along microtubules Pick-up：Takayuki Torisawa （National Institute of Genetics）
Lee-Wei Yang
Drug the Allosteric Site of a Cancer Target Revealed by Time-Dependent Linear Response Theory Speaker：Lee-Wei Yang （National Tsing Hua University）
Namiko Mitarai
Microbial competition in expanding colony: Emergent collective alignment gives an advantage to longer cells Speaker：Namiko Mitarai （The Niels Bohr Institute, University of Copenhagen）
Stefano Bo
Single-molecule dynamics across phase boundaries in active biomolecular condensates Speaker：Stefano Bo （King's College London）

Symposium 27

DNA/Chromatin Physics

16:00-18:20, Thu. 27 June    Room B-2

Tsuyoshi Terakawa
Unveiling the Molecular Mechanism of Histone Recycling through Biophysical Approaches Chair / Speaker：Tsuyoshi Terakawa （Kyoto University）
Eric C. Greene
New Paradigms for Rad51 paralog function Chair / Speaker：Eric C. Greene （Columbia University）
Shixin Liu
Machines on Genes: A Single-Molecule Perspective Speaker：Shixin Liu （The Rockefeller University）
Jong-Bong Lee
Mismatch Elimination in human DNA mismatch repair Speaker：Jong-Bong Lee （POSTECH）
Guang Zhu
G-quadruplex Structures Formed by Human Telomeric and C9orf72 DNA and RNA Speaker：Guang Zhu （The Hong Kong University of Science and Technology）

Symposium 28

Membraneless Organella, Autophage, Liquid-liquid Phase Separation

16:00-18:20, Thu. 27 June    Room C-2

Arslan Siddique
Chair：
Arslan Siddique（University of New South Wales）
Miho Yanagisawa
How does membrane confinement at the cell size change the phase separation of macromolecules? Chair / Speaker：Miho Yanagisawa （University of Tokyo）
Anderson Ho Cheung Shum
Cell-inspired biomimetic droplets Speaker：Anderson Ho Cheung Shum （Advanced Biomedical Instrumentation Centre & The University of Hong Kong）
Roland L. Knorr
Capillary force in cells: functional bio-condensate wetting Speaker：Roland L. Knorr （Humboldt-Universität zu Berlin）
Zhi Qi
Deciphering the molecular mechanism of DNA-protein interactive co-condensates Pick-up：Zhi Qi （Peking University）
Yi Shen
Condensates’ interface triggers the liquid-to-solid transition Speaker：Yi Shen （University of Sydney）

Symposium 29

Soft Matter Biophysics

16:00-18:20, Thu. 27 June    Room D

Masaki Sasai
Chair：
Masaki Sasai（Kyoto University）
Amin Doostmohammadi
Active Topological Defects and Universal Symmetries in Living Biological Matter Speaker：Amin Doostmohammadi （University of Copenhagen）
Daniel Jost
On the role of polymerases in shaping the 4D Genome Speaker：Daniel Jost （CNRS - ENS de Lyon）
Shin Fujishiro
Formation of chromatin domains without loop extrusion: the chromatin capture model of interphase cohesin Pick-up：Shin Fujishiro （Kyoto University, Japan）
Patricia Bassereau
Lipid membranes and membrane proteins: Not a coexistence but an intimate relationship. Chair / Speaker：Patricia Bassereau （Institut Curie）
Dolores Bozovic
Nonlinear Dynamics of the Auditory System Speaker：Dolores Bozovic （University of California Los Angeles）

Symposium 30

Structure, Function and Biophysics of the Bacterial Motility and Flagellar Motor

10:00-12:20, Fri. 28 June    Room B-1

Seiji Kojima
Chair：
Seiji Kojima（Nagoya University）
Ashley Nord
Spatio-temporal dynamics of the proton motive force on single bacterial cells Speaker：Ashley Nord （Centre de Biologie Structurale）
Wing Ngor Shannon Au
Diversity of flagellar system – What do we learn from H. pylori? Speaker：Wing Ngor Shannon Au （Chinese University of Hong Kong）
Nicholas Taylor
5:2 molecular motors – from bacterial motility to anti-phage defense Speaker：Nicholas Taylor （University of Copenhagen）
Shuichi Nakamura
Adhesins and flagella-dependent bacterial surface motility Speaker：Shuichi Nakamura （Tohoku University）
xxxxx
A cell-surface conveyor belt controls the rotational direction of its driver Speaker：Abhishek Shrivastava （Arisona State University）
Matthew Baker
Protein engineering via directed evolution of the stator subunit of the bacterial flagellar motor Chair / Speaker：Matthew Baker （University of New South Wales）

Symposium 31

Stem Cells and Organoids

10:00-12:20, Fri. 28 June    Room B-2

Minoru Takasato
Generation of Urinary Tract Organoids from Human Pluripotent Stem Cells Chair / Speaker：Minoru Takasato （RIKEN）
Genki Kanda
Tailoring autonomous trial-and-error by robots and AI (robotic search system) for Biophysics Pick-up：Genki Kanda （RIKEN）
xxxxx
3D human neural organoid models for interrogating mechanisms and therapeutics in neurodegeneration Chair / Speaker：Andras Lakatos （University of Cambridge）
xxxxx
Hepato-Biliary-Pancreatic Organogenesis in a Dis Speaker：Takanori Takebe （Cincinnati Children's Hospital Medical Center）
Ruri Maekawa
Large-scale generation of uniform-sized miniature adipocyte spheroids in hydrogel capsules Pick-up：Ruri Maekawa （The Univerisy of Tokyo）
Yumi Konagaya
A state of partial Rb inactivation and intermediate E2F activation safeguards proliferation commitment Speaker：Yumi Konagaya （RIKEN Center for Biosystems Dynamics Research (BDR)）

Symposium 32

Origin of Life

10:00-12:20, Fri. 28 June    Room D

Ryo Mizuuchi
Chair：
Ryo Mizuuchi（Waseda University）
Tony Z. Jia
Chair：
Tony Z. Jia（Tokyo Institute of Technology）
Moran Frenkel-Pinter
Evolution of Complex Chemical Mixtures Reveals Combinatorial Compression and Population Synchronicity Speaker：Moran Frenkel-Pinter （The Hebrew University of Jerusalem）
Tomoko Yamaguchi
The peptides increase the compartmentalization and stability of the protoribosome Pick-up：Tomoko Yamaguchi （Graduate School of Pharmaceutical Sciences, Kyoto University）
Arslan Siddique
Investigating Biophysical Impacts of Prebiotic Milieu on the Membrane Stability using Model Systems Speaker：Arslan Siddique （University of New South Wales）
Seung Soo Oh
In vitro selection of primitive catalysts to fill the gap between chemical and enzymatic RNA self-replication systems Speaker：Seung Soo Oh （Pohang University of Science and Technology）
Shunsuke Tagami
Reconstruction of Ancient Protein Folds in the Central Dogma Machinery Speaker：Shunsuke Tagami （RIKEN）

Symposium 33

Data Sharing and Open Science

10:00-12:20, Fri. 28 June    Room E

Shuichi Onami
SSBD and Global Sharing of Bioimaging Data Chair / Speaker：Shuichi Onami （RIKEN Center for Biosystems Dynamics Research）
Caterina Strambio-De-Castillia
Managing the image-data life cycle for the real world: connecting the dots from sample preparation to image acquisition, analysis, publication, and data reuse Chair / Speaker：Caterina Strambio-De-Castillia （University of Massachusetts Chan Medical School）
TPingsheng Liu
Chinese Cohort Studies and Data Sharing Speaker：Pingsheng Liu （Institue of Biophysics, CAS）
Oluwaseun F. Gakenou
GEMS Informatics: advancing data-driven innovation in agri-food and natural resources management . Speaker：Oluwaseun F. Gakenou （Stellenbosch University）
Josh Moore
Scalable strategies for a next-generation of FAIR bioimaging Speaker：Josh Moore （German BioImaging (GerBi)/ Open Microscopy Environment (OME)）

Hands-on Training Session

Hands-on Training Session - D

DNA Nanomachine Tutorial

14:30-16:50, Mon. 24 June    Room C-2

xxxxxx
Chair：
Shin-ichiro Nomura（Tohoku University）
Masayuki Endo
DNA origami-based integrated molecular systems and functional nanomachines Speaker：Masayuki Endo （Kansai University）
Akinori Kuzuya
Nanomechanical DNA Origami Devices Speaker：Akinori Kuzuya （Kansai University）
Yuki Suzuki
Multi-reconfigurable and multi-responsive DNA origami nanodevices Speaker：Yuki Suzuki （Mie University）
Ibuki Kawamata
Online user interface of computational tools for accelerating DNA nanotechnology research Speaker：Ibuki Kawamata （Kyoto University）
Nathan Nunes Evangelista
Long DNA strands’ insertion into DNA droplets as a potential model for chromatin condensates studies Pick-up：Nathan Nunes Evangelista （Tokyo Institute of Technology）
Hiromu Akai
DNA nanopore sensor for cell secretion measurement Pick-up：Hiromu Akai （Nagaoka University of Technology）

Hands-on Training Session - A

Millions of Single Live Cell Analysis with the Automated Trans-scale-scope, AMATERAS

16:00-18:20, Tue. 25 June    Room C-2

Takeharu Nagai
Automated trans-scale scope opens up a new horizon in life science research Chair / Speaker：Takeharu Nagai （Osaka University）
Mako Kamiya
Activatable Raman probes for multiplexed vibrational imaging in live cells and tissues Speaker：Mako Kamiya （Tokyo Institute of Technology）
Robert E. Campbell
Engineering high performance biosensors to analyze signaling and metabolism in live cells Speaker：Robert E. Campbell （The University of Tokyo）
Imari Sato
Analyzing the Invisible: Advanced Techniques in Microscopy and Spectroscopy for Internal State Characterization Speaker：Imari Sato （National Institute of Informatics）
Shuichi Onami
Cell Tracking and Data Management for AMATERAS Chair / Speaker：Shuichi Onami （RIKEN Center for Biosystems Dynamics Research）

Hands-on Training Session - B

Visualizing the Nanometer World in Liquid by Bio-SPMs

10:00-12:20, Thu. 27 June    Room E

xxxxxx
Chair：
Noriyuki Kodera（Kanazawa University）
Takeshi Fukuma
Visualizing Nanoscale Dynamics and Mechanics in Living Cells by Nanoendoscopy AFM Speaker：Takeshi Fukuma （Kanazawa University）
Keisuke Miyazawa
Nanoscale analysis of microbial cell walls using AFM Speaker：Keisuke Miyazawa （Kanazawa University）
xxxxx
Visualizing surface dynamics of living cells at nanometer scale resolution with scanning ion conductance microscopy Speaker：Shinji Watanabe （Nano Life Science Institute, Kanazawa University）
Kan Shoji
Biological Nanopore Probes for Scanning Ion Conductance Microscopy Speaker：Kan Shoji （Nagaoka University of Technology）
Mikihiro Shibata
Single-molecule imaging of AMPA-type glutamate receptors by high-speed atomic force microscopy Speaker：Mikihiro Shibata （Kanazawa University）
Ikuko Hayashi
HS-AFM analysis of microtubule-binding proteins in solution Speaker：Ikuko Hayashi （Yokohama City University）

Hands-on Training Session - E

Exploring Multi-cellular Mechanics

10:00-12:20, Fri. 28 June    Room A

Tatsuo Shibata
Chair：
Tatsuo Shibata（RIKEN）
H. Yoshimura
Chair：
Shige H. Yoshimura（Kyoto University）
xxxxx
Active cytoskeleton controlled through force and shape Speaker：Yusuke Maeda （Kyushu University）
Tomoki Ishibashi
Cellular-level left-right asymmetry, cell chirality, induces the chiral collective rotation of multicellular colony Speaker：Tomoki Ishibashi （RIKEN）
xxxxx
Analysis of Differential Growth in Curved Surface Morphogenesis through Constructing a Conformal Map Pick-up：Kentaro Morikawa （Kyoto University）
Makoto Sato
Tiling mechanisms of the compound eye through geometrical tessellation Chair / Speaker：Makoto Sato （Kanazawa University）
Fu-Lai Wen
Mechanical waves decode positional information to calibrate wound healing response in zebrafish Speaker：Fu-Lai Wen （National Taipei University of Education）
xxxxx
PIEZO1-mediated mechanosensing regulates the fate of neural progenitor cells during cerebral development Speaker：Mayumi Okamoto （Nara Women's University）

Hands-on Training Session - C

CHARMM-GUI/GENESIS MD Tutorial

10:00-12:20, Fri. 28 June    Room C-2

Yuji Sugita
Chair：
Yuji Sugita（RIKEN）
Helmut Grubmuller
Three routes to molecular movies Speaker：Helmut Grubmuller （Max Planck Institute for Multidisciplinary Sciences）
Chen Song
Modeling multi-state structures of proteins and simulating their conformational transitions Speaker：Chen Song （Peking University）
Kwangho Nam
Multiscale Simulations of Enzyme Mechanisms: Bridging Catalysis, Conformational Changes and Ligand Release Speaker：Kwangho Nam （University of Texas at Arlington）
Song-ho Chong
Exploring Allosteric Changes in the Conformational Landscape of Src Kinase upon Substrate Binding by GENESIS Speaker：Song-ho Chong （Kumamoto University）
Giovanni Brandani
Computational Explorations of Chromatin Structure and Dynamics: from Single Nucleosomes to Entire Genes Speaker：Giovanni Brandani （Kyoto University）
Wonpil Im
WHAT CAN CHARMM-GUI DO FOR YOU? Chair / Speaker：Wonpil Im （Lehigh University）

Poster

ABA Symposium

Symposium 38

Asian Biophysics Association (ABA) Symposium

16:00-18:20, Thu. 27 June    Room E

Elizabeth Hinde
Speaker：Elizabeth Hinde （The University of Melbourne）
Pingsheng Liu
Speaker：Pingsheng Liu （Institue of Biophysics, CAS）
Haibin Su
Chair / Speaker：Haibin Su （HKUST）
Ruchi Anand
Speaker：Ruchi Anand （Indian Institute of Technology Bombay）
Satoshi Takahashi
Speaker：Satoshi Takahashi （Tohoku University）
Hyun-Ho Lim
Speaker：Hyun-Ho Lim （Korea Brain Research Institute (KBRI)）
Shang-Te Danny Hsu
Chair / Speaker：Shang-Te Danny Hsu （Academia Sinica）
Tetsuhiro S. Hatakeyama
ABA Young Investigator Award: Deciphering the Complexity in Biological Interaction Awardee：Tetsuhiro S. Hatakeyama （Tokyo Insitute of Technology）

Morning Seminar

Morning Seminar 01 (Avanti Polar Lipids)

Delicious Molecules: A Primer on Lipids and Membrane Biophysics

8:00-8:50,Tue. 25 June    Room A

Delicious molecules: A primer on lipids and membrane biophysics
Chair/Speaker 1： Chiho Watanabe （Hiroshima University, Japan）
Chair/Speaker 2： Roberto Covino （Frankfurt Institute for Advanced Studies, Germany）

Morning Seminar 02 (GeneFrontier)

Introduction of the reconstituted cell-free protein synthesis system, the PURE system, for synthetic biology research

8:00-8:50, Wed. 26 June    Room A

Chair：
Takashi Kanamori（GeneFrontier Corporation）
A reconstituted cell-free protein synthesis for synthetic biology research: gene regulation to artificial cell synthesis Speaker： Tomoaki Matsuura （Tokyo Institute of Technology）

Morning Seminar 03 (Avanti Polar Lipids)

PROTEIN AGGREGATION AND DISEASES

8:00-8:50, Thu. 27 June    Room A

PROTEIN AGGREGATION AND DISEASES
Chair/Speaker 1： Motomasa Tanaka （RIKEN Center for Brain Science）
Speaker 2： Lukasz A. Joachimiak （University of Texas Southwestern Medical Center）
Speaker 3： Eri Chatani （Graduate School of Science, Kobe University）

BP Seminar

BP Seminar 01 (JEOL Ltd.)

Microscope Technology that Realizes Structural Biology

12:35-13:35, Tue. 25 June    Room A

Chair：
Akio Sekigawa（JEOL Ltd.）
Introduction of high throughput and high flexible workflows of cryo-TEM Speaker 1：Naoki Hosogi （JEOL Ltd.）
Introduction of newly developed cryo-FIB for cryo-TEM Speaker 2：Noriaki Mizuno （JEOL Ltd.）

BP Seminar 02 (Carl Zeiss Co., Ltd.)

Investigate Molecular Dynamics in Live Cells and Organisms using Fluorescence Correlation-based Microscopy Methods

12:35-13:35, Tue. 25 June    Room B-1

Chair：
Akira Sato（ZEISS Research Microscopy Solutions, Japan）
Investigate Molecular Dynamics in Live Cells and Organisms using Fluorescence Correlation-based Microscopy Methods Speaker：Xianke Shi （ZEISS Research Microscopy Solutions, APAC）

BP Seminar 03 (Leica Microsystems K.K.)

To The Future of Microscopy Imaging

12:35-13:35, Tue. 25 June    Room B-2

Chair：
Shintaro Tanaka（Leica Microsystems K.K.）
Intracellular temperature mapping using high-speed fluorescence lifetime imaging microscopy Speaker 1：Kohki Okabe （Graduate School of Pharmaceutical Sciences, The University of Tokyo）
STELLARIS enables the fluorescence lifetime imaging, ranging from FRET and Biosensors to Super-resolution microscopy Speaker 2： Suguru Osari （Leica Microsystems K.K.）

BP Seminar 04 (Nakatani Foundation for Advancement of Measuring Technologies in Biomedical Engineering)

Unveil the Spark: Explore the Decision Moment to become Biophysicists!

12:35-13:35, Tue. 25 June    Room C-2

Unveil the Spark: Explore the Decision Moment to become Biophysicists!
Chair：
Satoshi Takahashi（Tohoku University）
Chair：
Seiji Kojima（Nagoya University）
Chair：
Ikuko Fujiwara（Nagaoka Univresity of Technology）
Speaker 1：Elizabeth Hinde （University of Melbourne）
Speaker 2：Yoshie Harada （Osaka Universitry）
Speaker 3：Heeyoun Bunch （Kyungpook National University）

BP Seminar 05 (SIGMAKOKI CO., LTD.)

A New World from Single Cells to Cell Populations Revealed by the Ultra-wide-field Microscope "AMATERAS"

12:35-13:35, Tue. 25 June    Room D

Chair：
Nobutoyo Oguni（SIGMAKOKI CO., LTD.）
Development of trans-scale scope “AMATERAS” and direct observation of millions of cellular dynamics Speaker 1：Taro Ichimura （Osaka University）
Introducing a new product of wide-field microscope "CUS-WF" that can be installed in each laboratory Speaker 2：Yuichi Inoue （SIGMAKOKI CO., LTD.）

BP Seminar 06 (On-chip Biotechnologies Co., Ltd)

BarBIQ: a novel method for single-cell-based quantitative analysis of bacterial microbiota using droplets

12:35-13:35, Tue. 25 June    Room E

Chair：
Kageyasu Takanashi（On-chip Biotechnologies Co., Ltd.）
BarBIQ: accurate identification and quantification of bacterial cells in the microbiota using droplets and cellular barcoding Speaker： Katsuyuki Shiroguchi （RIKEN Center for Biosystems Dynamics Research (BDR), Japan）

BP Seminar 07 (Refeyn)

Mass Photometry – Revolutionary Biophysical Characterization of Single Molecules

12:35-13:35, Wed. 26 June    Room A

Chair：
Kohei Shiba（Refeyn Japan, K.K.）
Mass photometry – revolutionary biophysical characterization of single molecules Speaker： Tomás de Garay （Refeyn Ltd.）

BP Seminar 08 (HAMAMATSU PHOTONICS K.K.))

Nanoscale Quantum Biosensors: Imaging Techniques for Measurement

12:35-13:35, Wed. 26 June    Room B-1

Nanoscale Quantum Biosensors: Imaging Techniques for Measurement Speaker： Ryuji Igarashi （Institute for Quantum Life Science, National Institutes for Quantum Science and Technology）

BP Seminar 09 (Yokogawa Electric Corporation)

The Story behind the Invention of the Confocal Scanner CSU

12:35-13:35, Wed. 26 June    Room D

Chair：
Toshiaki Endou（Yokogawa Electric Corporation）
Chair：
Yoshitaka Sekizawa（Yokogawa Electric Corporation）
The story behind the invention of the confocal scanner CSU Speaker 1： Takeo Tanaami （Yokogawa Electric Corporation）
N/A Nagisa Katou （Yokogawa Electric Corporation）

BP Seminar 10 (Digital Bioassay Laboratory, The University of Tokyo and TOPPAN Holdings Inc.)

Digital Bioassay Laboratory in Univ. Tokyo

12:35-13:35, Wed. 26 June    Room E

Chair：
Yoichi Makino（Technical Research Institute, TOPPAN Holdings Inc.）
Digital bioassay for analyzing Alzheimer’s amyloid β-bound extracellular vesicles Speaker 1： Kohei Yuyama （Faculty of Advanced Life Science, Hokkaido University）
Applications of Digital Bioassay Speaker 2： Yoshihiro Minagawa （Department of Applied Chemistry, Graduate School of Engineering, The University of Tokyo, Digital Bioanalysis Laboratory, The University of Tokyo）

BP Seminar 11 (NIKON SOLUTIONS CO.,LTD.)

From VAAS to NSPARC: 15 Years of Super-Resolution Confocal Microscopy

12:35-13:35, Thu. 27 June    Room A

Chair：
Tatsuo Fukui（NIKON SOLUTIONS CO.,LTD.）
From VAAS to NSPARC: 15 Years of Super-Resolution Confocal Microscopy Speaker 1： Yasushi Okada （RIKEN Center for Biosystems Dynamics Research (BDR), Department of Cell Biology, Graduate School of Medicine, the University of Tokyo, Department of Physics, Universal Biology Institute (UBI) and International Research Center for Neurointelligence (WPI-IRCN), the University of Tokyo）

BP Seminar 12 (Refeyn)

Mass Photometry – Revolutionary Biophysical Characterization of Single Molecules

12:35-13:35, Thu. 27 June    Room B-1

Chair：
Kohei Shiba（Refeyn Japan, K.K.）
Applications for protein assembly and biophysical characterization by mass photometry Speaker： Tomás de Garay （Refeyn Ltd.）

BP Seminar 13 (Evident Corperation)

Reconstitution of actin cytoskeletal dynamics and functions

12:35-13:35, Thu. 27 June    Room D

Reconstitution of actin cytoskeletal dynamics and functions Speaker： Makito Miyazaki （RIKEN Center for Biosystems Dynamics Research）

BP Seminar 14 (Twist Bioscience)

WeMakeDNA - Approaches to Optogenetics Using Synthetic Genes

12:35-13:35, Thu. 27 June    Room E

Chair：
Masanori Noguchi（Twist Bioscience）
Structural and Functional Analysis of Light-Gated Ion Channels Assisted by Rapid DNA Synthesis Services Speaker 1： Hideaki Kato （The Uniersity of Tokyo）
Speaker 2： Kazuki Kaneshiro （Twist Bioscience）

BP Seminar 15 (The Biophysical Society of Japan & Acaric.co.ltd.)

Beyond Borders: Insights into International Employment Opportunities

12:35-13:35, Fri. 28 June    Room A

Chair：
Daisuke Nakane（Committee for Gender Equality and Support for Young Researchers, The Biophysical Society of Japan）
Chair：
Takayuki Nishizaka（Committee for Gender Equality and Support for Young Researchers, The Biophysical Society of Japan）
Global Employment Trends and Application Tips Speaker 1： Toshiaki Kaminaka （Acaric.co.ltd.）
Job Opportunities for Advanced Research Talents in Japanese Private Companies Speaker 2： Junko Tamaki （Acaric.co.ltd.）

BP Seminar 16 ("Nagoya Institute of Technology & SHIMADZU CORPORATION")

Introduction of Mass Spectrometry Imaging Technology

12:35-13:35, Fri. 28 June    Room B-2

Chair：
Kota Katayama（Graduate School of Engineering Nagoya Institute of Technology）
Introduction of Mass Spectrometry Imaging Technology Speaker： Eiichi Matsuo （Analytical & Measuring Instruments Division Shimadzu Corporation）

Sponsored Symposium

Sponsored Symposium 01: Physics and Mechanobiology in Cellular and Extracellular Systems

Physics and Mechanobiology in Cellular and Extracellular Systems
Sponsor: MEXT KAKENHI Grant-in-Aid for Transformative Research Area (A) "Material properties determine body shapes and their constructions"
MEXT KAKENHI Grant-in-Aid for Transformative Research Area (A) "Integration of Extracellular Information by Multimodal ECM Activity"

16:00-18:20, Tue. 25 June    Room D

Statistical mechanics approach to cell-substrate interactions Chair 1/Speaker 3： Shinji Deguchi （Osaka University）
The Role of Environmental Asymmetry in Epithelial Tissue Chair 2/Speaker 4： Yasuhiro Inoue （Kyoto University）
Molecular mechanisms regulating mechanotransduction at cell adhesions Speaker 1： Cristina Bertocchi （Pontificia Universidad Católica de Chile）
Dissecting the Mechanical and Dynamic Behaviors of Cells in Silico Speaker 2： Taeyoon Kim （Purdue University）

Sponsored Symposium 02: Exploring the Dynamics of Biomolecular Supra-Assemblies

Exploring the Dynamics of Biomolecular Supra-Assemblies:
Sponsor: JST PRESTO, Dynamic supra-assembly of biomolecular systems

16:00-18:20, Thu. 27 June    Room A

Chair：
Hideki Nakamura（Kyoto University）
Manipulating and elucidating the nucleation process of biomolecular condensates in living cells Chair 2/Speaker 5： Shunsuke Shimobayashi （Kyoto University）
Molecular dynamics of intrinsically disordered proteins within protein condensates Chair 3/Speaker 6： Eiji Yamamoto （Keio University）
Challenging the frontiers of single-molecule or super-resolution live-cell Imaging Speaker 1： Yasushi Okada （The University of Tokyo）
Liquid-Liquid phase separation and synaptic plasticity Speaker 2： Yasunori Hayashi （Kyoto University Graduate School of Medicine）
Dynamics of phase separated protein condensate materials Speaker 3： Yongwon Jung （Korea Advanced Institute of Science and Technology (KAIST)）
Mega-scale experimental analysis of protein folding stability in biology and design Speaker 4： Kotaro Tsuboyama （The University of Tokyo）