2023革新脳国際シンポジウム
第53回日本神経精神薬理学会年会サテライトシンポジウム
主催：理化学研究所脳神経科学研究センター
協賛：日本医療研究開発機構（AMED）
後援：日本神経精神薬理学会
AMED革新脳国際シンポジウム
神経変性メカニズム 2023：異常たんぱく質伝播とグリア細胞の役割
AMED Brain/MINDS International Symposium
Mechanism of Neurodegeneration 2023:
The roles of pathological protein propagation and glial cells
Time & Date: 10:00-16:10, Sunday, September 10, 2023
Venue: Tokyo Dome Hotel B1F シンシア
Organizers: AMED Brain/MINDS Neurodegenerative Diseases Group
10:00-10:05 Ryosuke Takahashi (Kyoto University) Opening Remarks
Session 1: Protein Propagation (1)
Co-Chair: Masato Hasegawa (TMiMS), Yuji Takahashi (NCNP)
10:05-10:25 Masanori Sawamura (Kyoto University)
Lewy body disease primate model with α-synuclein propagation from the olfactory bulb.
10:25-10:45 Ayami Okuzumi (Juntendo University)
A Research for mechanism and diagnosis of synucleinopathy based on prion-like seeding hypothesis.
10:45-11:05 Kousuke Baba (Osaka University)
Mutant α-syn fibrils induce Lewy-like pathology in mice.
11:05-11:15 Break
Session 2: Protein Propagation (2)
Co-Chair: Ryosuke Takahashi (Kyoto University), Nobutaka Hattori (Juntendo University)
11:15-12:00 Virginia Lee (University of Pennsylvania)
Transmission of Misfolded Proteins in Neurodegenerative Disorders: A Common Mechanism of Disease Progression
12:00-12:30 Masato Hasegawa (TMiMS)
Prion-like propagation of pathological proteins in neurodegenerative disorders.
12:30 -13:30 Lunchtime Break
Session 3: Glial Cells (1)
Co-Chair: Makoto Higuchi (QST), Taisuke Tomita (The University of Tokyo)
13:30-14:15 Li Gan (Cornell University)
Target innate immunity to enhance cognitive resilience in tauopathy.
14:15-14:45 Taisuke Tomita (The University of Tokyo)
Novel strategies for enhanced amyloid clearance in the Alzheimer disease brain.
14:45-15:00 Break
Session 4: Glial Cells (2)
Co-Chair: Makoto Higuchi (QST), Taisuke Tomita (The University of Tokyo)
15:00-15:30 Hiroaki Wake (Nagoya University)
15:30-16:00 Makoto Higuchi (QST)
Glial regulation of E-I balances in health and disease.
16:00-16:10 Toshihisa Ohtsuka (University of Yamanashi) Closing Remarks
Contact: symp2023@kuhp.kyoto-u.ac.jp
