2021 JCA-AACR Precision Cancer Medicine International Conference

Program

Live sessions will be recorded and available for On-Demand viewing from September 20, 2021.

Program DAY 1 Date/Time
(JST)
Date/Time
(PDT)
Date/Time
(EDT)

Keynote Session

Chair: Dr. Hiroyuki Mano
(National Cancer Center, Tokyo, Japan) (JCA)

Chair: Dr. Elaine R. Mardis
(Nationwide Children’s Hospital, Columbus, Ohio, USA) (AACR)

9/11 Sat.
8:00-8:55
9/10 Fri.
16:00-16:55
9/10 Fri.
19:00-19:55

KS-1: National Platform for Cancer Precision Medicine in Japan

Dr. Hiroyuki Mano
(National Cancer Center, Tokyo, Japan) (JCA)

KS-2: Genomics-Guided Pediatric Cancer Precision Medicine: New Developments

Dr. Elaine R. Mardis
(Nationwide Children’s Hospital, Columbus, Ohio, USA) (AACR)

Plenary 1:
Liquid Biopsy

Chair: Dr. Takayuki Yoshino
(National Cancer Center Hospital East, Chiba, Japan)

Chair: Dr. Lillian L. Siu
(UHN Princess Margaret Cancer Centre, Toronto, Ontario, Canada)

9/11 Sat.
9:00-10:45
9/10 Fri.
17:00-18:45
9/10 Fri.
20:00-21:45

PL1-1: Circulating DNA for Liquid Biopsies: Coming in Different Sizes and Shapes

Dr. Dennis Lo
(Chinese University of Hong Kong, Hong Kong, China-Hong Kong)

PL1-2: Exosomal PD-L1: Role in Immune Suppression and Potential Application in Immune Oncology

Dr. Wei Guo
(University of Pennsylvania, Philadelphia, Pennsylvania, USA)

PL1-3: Liquid Biopsy to Enable MRD Detection and Interception and the Precise Use of Immunotherapy

Dr. Lillian L. Siu
(UHN Princess Margaret Cancer Centre, Toronto, Ontario, Canada)

PL1-4: Near Future Forecast of Precision Oncology using Liquid Biopsy Technology

Dr. Takayuki Yoshino
(National Cancer Center Hospital East, Chiba, Japan)
Break

Program 1:
Somatic Mutations in Precancerous Tissue

Chair: Dr. Benjamin L. Ebert
(Dana-Farber Cancer Institute, Boston, Massachusetts, USA)

Chair: Dr. Seishi Ogawa
(Kyoto University, Kyoto, Japan)

Program 2:
Novel Platforms for Precision Medicine

Chair: Dr. Jeffrey W. Tyner
(OHSU Knight Cancer Institute, Portland, Oregon, USA)

Chair: Dr. Shinichi Yachida
(Osaka University, Osaka, Japan)

9/11 Sat.
11:00-12:30
9/10 Fri.
19:00-20:30
9/10 Fri.
22:00-23:30

PG01-1: Clonal Hematopoiesis and the Origins of Blood Cancers

Dr. Benjamin L. Ebert
(Dana-Farber Cancer Institute, Boston, Massachusetts, USA)

PG02-1: Spatial Immunoprofiling for Stratification of Cancer Patients for Immunotherapy

Dr. Shohei Koyama
(National Cancer Center, Tokyo)

PG01-2: Clonal Expansion in Apparently Normal Tissues

Dr. Seishi Ogawa
(Kyoto University, Kyoto, Japan)

PG02-2: Functional Genomics for Therapeutic Innovation in Hematologic Malignancies

Dr. Jeffrey W. Tyner
(OHSU Knight Cancer Institute, Portland, Oregon, USA)

PG01-3: Somatic Mutations in Normal Bronchial Epithelia

Dr. Kenichi Yoshida
(Wellcome Sanger Institute, Saffron Walden, United Kingdom)

PG02-3: Human Fecal Microbiome-Based Biomarkers for Colorectal Cancer (Live only)

Dr. Shinichi Yachida
(Osaka University, Osaka, Japan)
Break

SS-1A: Leading with Data: Tumor-informed ctDNA Testing across Cancer Types
Sponsored by Natera

Chair: Dr. Hiroya Taniguchi
(Aichi Cancer Center)

Speaker: Dr. Angel Rodriguez
(Natera)

SS-1B: Genomes for Precision Oncology
Sponsored by Illumina K.K.

Chair: Dr. Hiroyuki Mano
(National Cancer Center, Tokyo)

Speaker: Dr. David Bentley
(Illumina, Inc.)

9/11 Sat.
12:40-13:10
9/10 Fri.
20:40-21:10
9/10 Fri.
23:40-1:10(9/11)

SS-2A: A New Therapeutic Cancer Vaccine inducing Multifunctional Immunity, Artificial Adjuvant Vector Cells
Sponsored by Nippon Becton Dickinson Company, Ltd.

Chair: Dr. Norimitsu Kadowaki
(Faculty of Medicine, Kagawa University)

Speaker: Dr. Shin-ichiro Fujii
(Team Leader, Laboratory for Immunotherapy, Center for Integrative Medical Sciences, RIKEN
Vice Director, Program for Drug Discovery and Medical Technology Platforms, RIKEN)

SS-2B: Comprehensive Cancer Gene Profiling for Precision Oncology
Sponsored by Konica Minolta Precision Medicine Japan, Inc.

Chair: Dr. Shinji Kohsaka
(National Cancer Center, Tokyo)

Speaker: Dr. Hiroyuki Aburatani
(Research Center for Advanced Science and Technology, The University of Tokyo)

9/11 Sat.
13:15-13:45
9/10 Fri.
21:15-21:45
9/11 Sat.
1:15-1:45

SS-3A: Leading the Way in Target Enrichment: Exceptional Performance, Improved Efficiency and Rapid Customization of Targeted Methylation Sequencing
Sponsored by Twist Bioscience

Chair: Mr. Mark Dupal
(Senior Sales Director, Asia Pacific, Twist Bioscience)

Speaker: Mr. Bryan Hoglund
(Senior Manager, NGS Business Solutions, Twist Bioscience)

SS-3B: Considerations for Incorporating Biomarkers into Real World Dataset
Sponsored by Syapse Inc.

Chair: Dr. Hiroyuki Mano
(National Cancer Center, Tokyo)

Speaker: Dr. Anna Berry
(Syapse)

9/11 Sat.
13:50-14:20
9/10 Fri.
21:50-22:20
9/11 Sat.
1:50-2:20
Break

Program 3:
Drug Resistance

Chair: Dr. Ryohei Katayama
(The Cancer Chemotherapy Center, JFCR, Tokyo, Japan)

Program 4:
Germline Predisposition

Chair: Prof. Katsutoshi Oda
(Division of Integrative Genomics, Graduate School of Medicine, The University of Tokyo Director, Department of Clinical Genomics The University of Tokyo Hospital, Japan)

9/11 Sat.
14:30-16:00
9/10 Fri.
22:30-0:00(9/11)
9/11 Sat.
1:30-3:00

PG03-1: HDAC3 is a Targetable Mediator of Therapeutic Resistance in Non-small Cell Lung Cancer

Dr. Reuben J. Shaw
(Salk Institute, La Jolla, California, USA)

PG04-1: Large-scale Germline Sequencing of Hereditary Cancer Genes in >60,000 Cancer Patients and Controls

Dr. Yukihide Momozawa
(RIKEN Center for Integrative Medical Sciences Laboratory for Genotyping Development, Kanagawa, Japan)

PG03-2: Mechanisms of Intrinsic Resistance Mediated by Tumor
Microenvironment and Secreted Proteins in Non-small Cell Lung Cancer

Dr. Ryohei Katayama
(The Cancer Chemotherapy Center, JFCR, Tokyo, Japan)

PG04-2: High Throughput Functional Analysis for the Clinical Annotation in Cancer Genome Medicine

Dr. Shinji Kohsaka
(National Cancer Center, Tokyo)

PG03-3: RAS Proteins in Human Disease

Dr. Frank McCormick
(UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California, USA)

PG04-3: Germline Predispositions to Hematologic Malignancies

Dr. Courtney D. DiNardo
(UT MD Anderson Cancer Center, Houston, Texas, USA)
ePoster presentation is available all the time during the conference as well as On-demand distribution by December 31
Program DAY 2 Date/Time
(JST)
Date/Time
(PDT)
Date/Time
(EDT)

Plenary 2:
Immuno-oncology

Chair: Dr. Hiroyoshi Nishikawa
(National Cancer Center, Tokyo)

Chair: Dr. Elizabeth M. Jaffee
(Johns Hopkins University, Baltimore, Maryland, USA)

9/12 Sun.
8:00-9:45
9/11 Sat.
16:00-17:45
9/11 Sat.
19:00-20:45

PL2-1: Integrity of the IFN and MHC Signaling Pathways in Tumor Immunity and Therapy

Dr. Weiping Zou
(University of Michigan, Ann Arbor, Michigan, USA)

PL2-2: Immunosuppression by Regulatory T Cells in the Tumor Microenvironment

Dr. Hiroyoshi Nishikawa
(National Cancer Center, Tokyo)

PL2-3: Pancreatic Cancer Treatment in the Era of Precision Immunotherapy

Dr. Elizabeth M. Jaffee
(Johns Hopkins University, Baltimore, Maryland, USA)

PL2-4: Epigenetic Insights into T Cell Longevity for Optimal Adoptive Immunotherapy

Dr. Yuki Kagoya
(Aichi Cancer Center Research Institute, Nagoya, Japan)
Break

Program 5:
Hematology

Chair: Dr. Keisuke Kataoka
(Keio University School of Medicine, Tokyo, Japan)

Chair: Dr. Elli Papaemmanuil
(Memorial Sloan Kettering Cancer Center, New York, New York, USA)

Program 6:
Research Focused on Asian Cancers

Chair: Dr. Patrick Tan
(Cancer Science Institute of Singapore, NUS, Singapore, Singapore)

Chair: Dr. Nilofer S. Azad
(Johns Hopkins University, Baltimore, Maryland, USA)

9/12 Sun.
10:00-11:30
9/11 Sat.
18:00-19:30
9/11 Sat.
21:00-22:30

PG05-1: Multicellular Ecosystem in HTLV-1 Viral Carcinogenesis Revealed by Multi-omics Single-cell Analysis

Dr. Keisuke Kataoka
(Keio University School of Medicine, Tokyo, Japan)

PG06-1: Recent Advances in the (Epi)genomic Landscape of Gastric Cancer

Dr. Patrick Tan
(Cancer Science Institute of Singapore, NUS, Singapore, Singapore)

PG05-2: Population Genomic Studies to Advance Precision Medicine Practices in Myeloid Neoplasms

Dr. Elli Papaemmanuil
(Memorial Sloan Kettering Cancer Center, New York, New York, USA)

PG06-2: Trans-ethnic Driver Landscape of Gastric Cancer

Dr. Tatsuhiro Shibata
(The Institute of Medical Science, The University of Tokyo, Tokyo, Japan)

PG05-3: Understanding and Targeting Aberrant Splicing in Leukemias

Dr. Akihide Yoshimi
(Cancer RNA Research Unit, National Cancer Center Research Institute, Tokyo, Japan)

PG06-3: The Emerging Understanding of Phenotypes of Biliary Tract Cancers

Dr. Nilofer S. Azad
(Johns Hopkins University, Baltimore, Maryland, USA)
Break

SS-4A: WGS and WES with DNBSEQ Technology for Precision Oncology
Sponsored by JAPAN MGI TECH CO., LTD

Chair: Dr. Hiroyuki Mano
(National Cancer Center, Tokyo)

Speaker: Mr. Toby Huang
(BD Director at MGI)

Speaker: Prof. Steven Jones
(University of British Columbia)

SS-4B: Fecal Microbiome Profiling in the SCRUM-Japan MONSTAR-SCREEN Project Reveals Novel Connections between Tumor and Gut Microbiota
Sponsored by bitBiome, Inc.

Chair: Mr. Sunao Fujioka
(CBO (Chief Business Officer), bitBiome, Inc.)

Speaker: Dr. Riu Yamashita
(Translational Informatics, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center)

9/12 Sun.
11:40-12:10
9/11 Sat.
19:40-20:10
9/11 Sat.
22:40-23:10

SS-5A: Real World Data Insights for the Advancement of Precision Medicine
Sponsored by Flatiron Health K.K.

Chair: Dr. Takayuki Yoshino
(Department of Gastrointestinal Oncology, National Cancer Center Hospital East)

Speaker: Dr. Ivy Altomare
(Medical Director, Flatiron Health Inc.)

SS-5B: Precision Medicine in Cancer
Sponsored by Denka Company Limited

Chair: Dr. Hiroyuki Mano
(National Cancer Center, Tokyo)

Speaker: Prof. Raju Kucherlapati
(Harvard Medical School)

9/12 Sun.
12:15-12:45
9/11 Sat.
20:15-20:45
9/11 Sat.
23:15-23:45

SS-6A: Web-based Treatment Decision Support Tool for Precision Medicine
Sponsored by Molecular Health

Chair: Prof. Manabu Muto
(Kyoto University, Graduate School of Medicine)

Speaker: Prof. Masashi Kanai
(Kyoto University, Graduate School of Medicine)

9/12 Sun.
12:50-13:20
9/11 Sat.
20:50-21:20
9/11 Sat.
23:50-0:20(9/12)
Break

Program 7:
Cancer Model Systems

Chair: Dr. Akinobu Hamada
(National Cancer Center, Tokyo)

Chair: Dr. Calvin J. Kuo
(Stanford University, Stanford, California, USA)

Program 8:
Real-World Evidence in Precision Medicine

Chair: Dr. Takashi Kohno
(National Cancer Center, Tokyo)

9/12 Sun.
13:30-15:00
9/11 Sat.
21:30-23:00
9/12 Sun.
0:30-2:00

PG07-1: Modeling Tumor Tissue Complexity with 3D Bioprinting

Dr. Rosalie C. Sears
(Oregon Health & Science University, Portland, Oregon, USA)

PG08-1: Utilization of Large Scale Real-world Tumor Profiling Data Obtained from Daily Cancer Treatment

Dr. Takashi Kohno
(National Cancer Center, Tokyo)

PG07-2: Organoid Modeling of Tumor Genomes and Microenvironments (Live only)

Dr. Calvin J. Kuo
(Stanford University, Stanford, California, USA)

PG08-2: Real-World Evidence in K-MASTER Cancer Precision Medicine Program

Dr. Yeul Hong Kim
(Korea University, Seoul, Korea)

PG07-3: Drug Discovery and Development Research for New Anticancer Agents based on Pharmacokinetic and Pharmacodynamic Analysis using Patient-derived Xenograft (J-PDX) Library

Dr. Akinobu Hamada
(National Cancer Center, Tokyo)

PG08-3: AACR Project GENIE: Powering Precision Medicine through International Data-Sharing

Dr. Philippe L. Bedard
(UHN Princess Margaret Cancer Centre, USA)

Break

Program 9:
AI in Precision Medicine

Chair: Dr. Shunpei Ishikawa
(The University of Tokyo, Tokyo, Japan)

Chair: Dr. Trey Ideker
(UC San Diego, La Jolla, California, USA)

Program 10:
Pediatric Cancer

Chair: Dr. Junko Takita
(Kyoto University, Kyoto, Japan)

Chair: Dr. Michelle Haber
(Children's Cancer Institute, Sydney, Australia)

9/12 Sun.
15:15-16:45
9/11 Sat.
23:15-0:45(9/12)
9/12 Sun.
2:15 -3:45

PG09-1: Building the Mind of Cancer

Dr. Trey Ideker
(UC San Diego, La Jolla, California, USA)

PG10-1: Integrated Genetic and Epigenetic Analysis of Pediatric Cancers

Dr. Junko Takita
(Kyoto University, Kyoto, Japan)

PG09-2: Universal Encoding of Cancer Histology by Deep Neural Network

Dr. Shunpei Ishikawa
(The University of Tokyo, Tokyo, Japan)

PG10-2: Zero Childhood Cancer: A Whole of System National Approach to Improving Outcomes of Australian Children with Cancer through Precision Medicine

Dr. Michelle Haber
(Children's Cancer Institute, Sydney, Australia)

PG09-3: Convergence of Machine Learning and Genomics for Precision Cancer Medicine

Dr. Eliezer Van Allen
(Dana-Farber Cancer Institute, Boston, Massachusetts, USA)

PG10-3: Genomic Variants in Pediatric Cancer: Model for Relapse, Precision Medicine, and Data Sharing Ecosystem

Dr. Jinghui Zhang
(St. Jude Children's Research Hospital, Memphis, Tennessee, USA)

ePoster presentation is available all the time during the conference as well as On-demand distribution by December 31

Industry Sessions

Poster Sessions

Liquid Biopsy
Immuno-oncology
Hematology
Pediatric Cancer
Drug Resistance
Germline Predisposition
Novel Platforms for Precision Medicine
Research Focused on Asian Cancers
Real-World Evidence in Precision Medicine
Somatic Mutations in Precancerous Tissue
Cancer Model Systems
AI in Precision Medicine