Special Session 42
3月28日［日］09:45-11:15
|
| |
| |
Genetic Cardiovascular Disease -From Mechanism to Phenotype and GWAS
|
|
|
| |
| |
|
|
| |
Recent development in the genomic research with new technologies has contributed to the profound understanding of the pathophysiological basis of cardiovascular diseases. Pathological rare variants linked with rarer diseases (ie. cardiomyopathy) have been identified using whole exome/genome sequencing, and the genomic loci associated with common diseases (ie. myocardial infarction) are detected as a result of genome-wide association study (GWAS). The RNA sequencing at the single-cell level is a very powerful tool for dissecting the abnormalities in gene expressions in the heart tissue. In this session, we would like to introduce our recent works on the genomics for cardiovascular diseases and discuss the phenotypic consequences and functional mechanisms, which will help us understand the pathophysiology and acquire the theoretical basis for the near-future genomic medicine.
|
|
|
| |
| |
|
|
| |
| |
 |
|
Jonathan G. Seidman
Department of Genetics, Harvard Medical School, Boston, USA
|
|
 |
|
Hiroyuki Morita
Department of Cardiovascular Medicine, The University of Tokyo, Tokyo
|
|
|
| |
| |
| |
| |
|
|
| |
| |
|
|
Jonathan G. Seidman
Department of Genetics, Harvard Medical School, Boston, USA
|
|
 |
|
Yoshihiro Asano
Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita/font>
|
|
|
| |
| |
 |
|
Seitaro Nomura
Department of Cardiovascular Medicine, The University of Tokyo, Tokyo
|
|
 |
|
Kaoru Ito
Laboratory for Cardiovascular Genomics and Informatics, RIKEN Center for Integrative Medical Sciences, Yokohama
|
|
|
| |
| |
|
|