Special Session 31
3月27日[土]16:00-17:30
|
|
|
cGMP research from bench to bedside
|
|
|
|
|
|
|
|
The cGMP-PKG signaling pathway has emerged as a new therapeutic target for heart failure. Sacubitril/Valsartan (ARNI), Vericiguat (sGC stimulator) and PDE inhibitors all enhance cGMP-PKG, acting on nitric oxide (NO)-soluble guanylate cyclase (sGC) or natriuretic peptides (NPs)-particulate guanylate cyclase pathways. Importantly, the complexity of their pathway regulation leads to differential downstream molecular targets and thus physiological impacts. With the world-renowned experts in this field, this session will provide the cutting-edge of cGMP research. We will discuss how we should use cGMP-modifying interventions to best strategize heart failure treatment.
|
|
|
|
|
|
|
|
|
 |
|
Eiki Takimoto
Department of Cardiovascular medicine, The University of Tokyo, Tokyo
|
|
 |
|
Burkert Pieske
Medical Clinic with focus on Cardiology, Charite Universitatsmedizin Berlin, Berlin, Germany
|
|
|
|
|
|
|
|
|
 |
|
Burkert Pieske
Medical Clinic with focus on Cardiology, Charite Universitatsmedizin Berlin, Berlin, Germany
|
|
 |
|
Michaela Kuhn
Institute of Cardiovascular Physiology, University of Wuerzburg, Wuerzburg, Germany
|
|
|
|
|
 |
|
Hitoshi Nakagawa
Department of Cardiovascular Medicine, Nara Medical University, Kashihara
|
|
 |
|
Nobuaki Fukuma
Division of Cardiology, Medical Department, Columbia University Vagelos College of Physicians and Surgeons, New York, USA
|
|
|
|
|
 |
|
Taishi Nakamura
Department of Medical Information Science and Administration Planning, Kumamoto University Hospital, Kumamoto
|
|
|
|
|
|
|
|
|
|